Targeting the EGFR/PCNA Signaling Suppresses Tumor Growth of Triple-Negative Breast Cancer Cells with Cell-Penetrating PCNA Peptides

Tyrosine 211 (Y211) phosphorylation of proliferation cell nuclear antigen (PCNA) coincides with pronounced cancer cell proliferation and correlates with poor survival of breast cancer patients. In epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-resistant cells, both nuclear E...

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Detalhes bibliográficos
Main Authors: Yu, Yung-Luen, Chou, Ruey-Hwang, Liang, Jia-Hong, Chang, Wei-Jung, Su, Kuo-Jung, Tseng, Yen-Ju, Huang, Wei-Chien, Wang, Shao-Chun, Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620387/
https://ncbi.nlm.nih.gov/pubmed/23593472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061362
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