Targeting the EGFR/PCNA Signaling Suppresses Tumor Growth of Triple-Negative Breast Cancer Cells with Cell-Penetrating PCNA Peptides

Tyrosine 211 (Y211) phosphorylation of proliferation cell nuclear antigen (PCNA) coincides with pronounced cancer cell proliferation and correlates with poor survival of breast cancer patients. In epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-resistant cells, both nuclear E...

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Hlavní autoři: Yu, Yung-Luen, Chou, Ruey-Hwang, Liang, Jia-Hong, Chang, Wei-Jung, Su, Kuo-Jung, Tseng, Yen-Ju, Huang, Wei-Chien, Wang, Shao-Chun, Hung, Mien-Chie
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620387/
https://ncbi.nlm.nih.gov/pubmed/23593472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061362
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