Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation

Epidermal growth factor receptor (EGFR) can undergo post-translational modifications, including phosphorylation, glycosylation and ubiquitylation, leading to diverse physiological consequences and modulation of its biological activity. There is increasing evidence that methylation may parallel other...

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Detalhes bibliográficos
Main Authors: Hsu, Jung-Mao, Chen, Chun-Te, Chou, Chao-Kai, Kuo, Hsu-Ping, Li, Long-Yuan, Lin, Chun-Yi, Lee, Hong-Jen, Wang, Ying-Nai, Liu, Mo, Liao, Hsin-Wei, Shi, Bin, Lai, Chien-Chen, Bedford, Mark T., Tsai, Chang-Hai, Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048027/
https://ncbi.nlm.nih.gov/pubmed/21258366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2158
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