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Caspase-independent cell death is involved in the negative effect of EGFR inhibitors on cisplatin in non-small cell lung cancer cells
PURPOSE: Results of multiple clinical trials suggest that EGFR tyrosine kinase inhibitors (TKIs) exhibit negative effects on platinum-based chemotherapy in lung cancer patients with wild type (wt) EGFR, but the underlying molecular mechanisms are still uncertain. Studies that identify the mechanism...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703145/ https://ncbi.nlm.nih.gov/pubmed/23344263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2621 |
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