The BRCA1-interacting protein, Abraxas, is required for genomic stability and tumor suppression

Germline mutations of BRCA1 confer hereditary susceptibility to breast and ovarian cancer. However, somatic mutation of BRCA1 is infrequent in sporadic breast cancers. The BRCA1 protein C-terminus BRCT domains interact with multiple proteins and are required for BRCA1's tumor suppressor functio...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Castillo, Andy, Paul, Atanu, Sun, Baohua, Huang, Ting Hsiang, Wang, Yucai, Yazinski, Stephanie A., Tyler, Jessica, Li, Lei, You, M James, Zou, Lee, Yao, Jun, Wang, Bin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149256/
https://ncbi.nlm.nih.gov/pubmed/25066119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.050
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items