The BRCA1-interacting protein, Abraxas, is required for genomic stability and tumor suppression

Germline mutations of BRCA1 confer hereditary susceptibility to breast and ovarian cancer. However, somatic mutation of BRCA1 is infrequent in sporadic breast cancers. The BRCA1 protein C-terminus BRCT domains interact with multiple proteins and are required for BRCA1's tumor suppressor functio...

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Detaylı Bibliyografya
Asıl Yazarlar: Castillo, Andy, Paul, Atanu, Sun, Baohua, Huang, Ting Hsiang, Wang, Yucai, Yazinski, Stephanie A., Tyler, Jessica, Li, Lei, You, M James, Zou, Lee, Yao, Jun, Wang, Bin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149256/
https://ncbi.nlm.nih.gov/pubmed/25066119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.050
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