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BRCA2 suppresses cell proliferation via stabilizing MAGE-D1

Germline mutations in BRCA2 gene predispose women to early-onset familial breast and ovarian cancer. BRCA2 is a protein of multiple functions. In addition to its role in DNA double-strand breaks repair, BRCA2 also plays a role in stabilization of stalled DNA replication forks, cytokinesis, transcrip...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tian, Xin-xia, Rai, Deepak, Li, Jun, Zou, Chaozhong, Bai, Yujie, Wazer, David, Band, Vimla, Gao, Qingshen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295243/
https://ncbi.nlm.nih.gov/pubmed/15930293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-0018
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