Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain tumor medulloblastoma. The need to reduce the risk of LMD has driven the development of aggressive tr...

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Dettagli Bibliografici
Autori principali: Jenkins, Noah C, Kalra, Ricky R, Dubuc, Adrian, Sivakumar, Walavan, Pedone, Carolyn A, Wu, Xiaochong, Taylor, Michael D, Fults, Daniel W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149244/
https://ncbi.nlm.nih.gov/pubmed/25059231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0085-y
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