Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain tumor medulloblastoma. The need to reduce the risk of LMD has driven the development of aggressive tr...

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Bibliografiske detaljer
Main Authors:	Jenkins, Noah C, Kalra, Ricky R, Dubuc, Adrian, Sivakumar, Walavan, Pedone, Carolyn A, Wu, Xiaochong, Taylor, Michael D, Fults, Daniel W
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2014
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4149244/ https://ncbi.nlm.nih.gov/pubmed/25059231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0085-y
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Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

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