Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain tumor medulloblastoma. The need to reduce the risk of LMD has driven the development of aggressive tr...

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Bibliographic Details
Main Authors:	Jenkins, Noah C, Kalra, Ricky R, Dubuc, Adrian, Sivakumar, Walavan, Pedone, Carolyn A, Wu, Xiaochong, Taylor, Michael D, Fults, Daniel W
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2014
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4149244/ https://ncbi.nlm.nih.gov/pubmed/25059231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0085-y
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Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

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