Llwytho...
WIP1 Enhances Tumor Formation in a Sonic Hedgehog–Dependent Model of Medulloblastoma
BACKGROUND: A significant number of medulloblastomas (MBs) originate from abnormal activation of the sonic hedgehog/patched (SHH/PTC) signaling pathway. Although p53 deficiency enhances tumor formation in mice, inactivation of the p53 gene is seen in a minority of MBs. Wild-type p53-induced phosphat...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607499/ https://ncbi.nlm.nih.gov/pubmed/22037313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/NEU.0b013e31823e5332 |
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