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Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma
Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain tumor medulloblastoma. The need to reduce the risk of LMD has driven the development of aggressive tr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149244/ https://ncbi.nlm.nih.gov/pubmed/25059231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0085-y |
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