Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain tumor medulloblastoma. The need to reduce the risk of LMD has driven the development of aggressive tr...

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Hlavní autoři: Jenkins, Noah C, Kalra, Ricky R, Dubuc, Adrian, Sivakumar, Walavan, Pedone, Carolyn A, Wu, Xiaochong, Taylor, Michael D, Fults, Daniel W
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149244/
https://ncbi.nlm.nih.gov/pubmed/25059231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0085-y
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