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Monomethylfumarate Induces γ-Globin Expression and Fetal Hemoglobin Production in Cultured Human Retinal Pigment Epithelial (RPE) and Erythroid Cells, and in Intact Retina

PURPOSE. Sickle retinopathy (SR) is a major cause of vision loss in sickle cell disease (SCD). There are no strategies to prevent SR and treatments are extremely limited. The present study evaluated (1) the retinal pigment epithelial (RPE) cell as a hemoglobin producer and novel cellular target for...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Promsote, Wanwisa, Makala, Levi, Li, Biaoru, Smith, Sylvia B., Singh, Nagendra, Ganapathy, Vadivel, Pace, Betty S., Martin, Pamela M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Association for Research in Vision and Ophthalmology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148926/
https://ncbi.nlm.nih.gov/pubmed/24825111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14179
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