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Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation

BACKGROUND: The fetal and adult globin genes in the human β-globin cluster on chromosome 11 are sequentially expressed to achieve normal hemoglobin switching during human development. The pharmacological induction of fetal γ-globin (HBG) to replace abnormal adult sickle β(S)-globin is a successful s...

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Bibliografski detalji
Glavni autori: Li, Biaoru, Ding, Lianghao, Li, Wei, Story, Michael D, Pace, Betty S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353202/
https://ncbi.nlm.nih.gov/pubmed/22537182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-153
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