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Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation
BACKGROUND: The fetal and adult globin genes in the human β-globin cluster on chromosome 11 are sequentially expressed to achieve normal hemoglobin switching during human development. The pharmacological induction of fetal γ-globin (HBG) to replace abnormal adult sickle β(S)-globin is a successful s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353202/ https://ncbi.nlm.nih.gov/pubmed/22537182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-153 |
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