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Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease
The developmental regulation of globin gene expression has shaped research efforts to establish therapeutic modalities for individuals affected with sickle cell disease and β-thalassemia. Fetal hemoglobin has been shown to block sickle hemoglobin S polymerization to improve symptoms of sickle cell d...
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| Veröffentlicht in: | Exp Biol Med (Maywood) |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SAGE Publications
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935285/ https://ncbi.nlm.nih.gov/pubmed/26283707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215596859 |
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