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Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease

The developmental regulation of globin gene expression has shaped research efforts to establish therapeutic modalities for individuals affected with sickle cell disease and β-thalassemia. Fetal hemoglobin has been shown to block sickle hemoglobin S polymerization to improve symptoms of sickle cell d...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Pace, Betty S, Liu, Li, Li, Biaoru, Makala, Levi H
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935285/
https://ncbi.nlm.nih.gov/pubmed/26283707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215596859
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