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FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors

Fetal hemoglobin (HbF) improves the clinical severity of sickle cell disease (SCD), therefore, research to identify HbF-inducing agents for treatment purposes is desirable. The focus of our study is to investigate the ability of FK228 analogues to induce HbF using a novel KU812 dual-luciferase repor...

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Détails bibliographiques
Auteurs principaux: Makala, Levi, Di Maro, Salvatore, Lou, Tzu-Fang, Sivanand, Sharanya, Ahn, Jung-Mo, Pace, Betty S.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359661/
https://ncbi.nlm.nih.gov/pubmed/22655179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/428137
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