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Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment

Renal cell carcinoma (RCC) is a heterogeneous disease with resistance to systemic chemotherapy. Elevated expression of multiple drug resistance (MDR) has been suggested to be one of the mechanisms for this resistance. Here, we provide an alternative mechanism to explain RCC's resistance to chem...

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Detalhes bibliográficos
Main Authors: Chen, Yumay, Chen, Chi-Fen, Polci, Rosaria, Wei, Randy, Riley, Daniel J., Chen, Phang-Lang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147323/
https://ncbi.nlm.nih.gov/pubmed/24970796
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