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Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment

Renal cell carcinoma (RCC) is a heterogeneous disease with resistance to systemic chemotherapy. Elevated expression of multiple drug resistance (MDR) has been suggested to be one of the mechanisms for this resistance. Here, we provide an alternative mechanism to explain RCC's resistance to chem...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Yumay, Chen, Chi-Fen, Polci, Rosaria, Wei, Randy, Riley, Daniel J., Chen, Phang-Lang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147323/
https://ncbi.nlm.nih.gov/pubmed/24970796
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