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Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control

Nek1, the first mammalian ortholog of the fungal protein kinase never in mitosis A, is involved early in the DNA damage sensing/repair pathway after ionizing radiation. Here we extend this finding by showing that Nek1 localizes to nuclear foci of DNA damage in response to many different types of dam...

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Hlavní autoři: Chen, Yumay, Chen, Phang-Lang, Chen, Chi-Fen, Jiang, Xianzhi, Riley, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597191/
https://ncbi.nlm.nih.gov/pubmed/18843199
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