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Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR
Never-in-mitosis A related protein kinase 1 (Nek1) is involved early in a DNA damage sensing/repair pathway. We have previously shown that cells without functional Nek1 fail to activate the more distal kinases Chk1 and Chk2 and fail to arrest properly at G(1)/S or M-phase checkpoints in response to...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173995/ https://ncbi.nlm.nih.gov/pubmed/21301226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.4.14814 |
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