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Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1

The mammalian NIMA-related protein kinase 1 (Nek1) is important for keeping cells alive after DNA damage, but the mechanism by which injured cells die without functional Nek1 has not yet been demonstrated. Here we show that Nek1 regulates the pathway to mitochondrial cell death through phosphorylati...

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Detalhes bibliográficos
Main Authors: Chen, Yumay, Craigen, William J., Riley, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673983/
https://ncbi.nlm.nih.gov/pubmed/19158487
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