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The TLK1/Nek1 axis contributes to mitochondrial integrity and apoptosis prevention via phosphorylation of VDAC1

The TLK1/Nek1 axis contributes to cell cycle arrest and implementation of the DDR to mediate survival upon DNA damage. However, when the damage is too severe, the cells typically are forced into apoptosis, and the contribution of TLKs in this process has not been investigated. In contrast, it is kno...

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Publicat a:Cell Cycle
Autors principals: Singh, Vibha, Khalil, Md Imtiaz, De Benedetti, Arrigo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028156/
https://ncbi.nlm.nih.gov/pubmed/31914854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1711317
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