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Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity
The Tousled Like kinases (TLKs) are involved in numerous cellular functions, including the DNA Damage Response (DDR), but only a handful of substrates have been identified thus far. Through a novel proteomic screen, we have now identified 165 human proteins interacting with TLK1, and we have focused...
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| Publicado en: | Cell Cycle |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5462085/ https://ncbi.nlm.nih.gov/pubmed/28426283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1314421 |
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