Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity

The Tousled Like kinases (TLKs) are involved in numerous cellular functions, including the DNA Damage Response (DDR), but only a handful of substrates have been identified thus far. Through a novel proteomic screen, we have now identified 165 human proteins interacting with TLK1, and we have focused...

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Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Singh, Vibha, Connelly, Zachary M., Shen, Xinggui, De Benedetti, Arrigo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2017
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Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462085/
https://ncbi.nlm.nih.gov/pubmed/28426283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1314421
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