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Defects of Mitochondrial DNA Replication
Mitochondrial DNA (mtDNA) is replicated by DNA polymerase γ in concert with accessory proteins such as the mitochondrial DNA helicase, single-stranded DNA binding protein, topoisomerase, and initiating factors. Defects in mtDNA replication or nucleotide metabolism can cause mitochondrial genetic dis...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146710/ https://ncbi.nlm.nih.gov/pubmed/24985751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0883073814537380 |
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