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Inherited Mitochondrial Diseases of DNA Replication
Mitochondrial genetic diseases can result from defects in mitochondrial DNA (mtDNA) in the form of deletions, point mutations, or depletion, which ultimately cause loss of oxidative phosphorylation. These mutations may be spontaneous, maternally inherited, or a result of inherited nuclear defects in...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271032/ https://ncbi.nlm.nih.gov/pubmed/17892433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.med.59.053006.104646 |
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