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ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint
The spindle assembly checkpoint (SAC), which blocks anaphase onset until all chromosomes have bi-oriented, is one of the key self-monitoring systems of the eukaryotic cell cycle for genome stability. The mitotic arrest-deficient protein 1 (Mad1), a critical component of the SAC, is hyperphosphorylat...
Gorde:
Egile Nagusiak: | , , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Oxford University Press
2014
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146412/ https://ncbi.nlm.nih.gov/pubmed/24728176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu087 |
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