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Cytotoxic and mutagenic properties of regioisomeric O (2)-, N3- and O (4)-ethylthymidines in bacterial cells
Exposure to environmental agents and endogenous metabolism can both give rise to DNA alkylation. Thymine is known to be alkylated at O (2), N3 and O (4) positions; however, it remains poorly explored how the regioisomeric alkylated thymidine lesions compromise the flow of genetic information by pert...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146411/ https://ncbi.nlm.nih.gov/pubmed/24710626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu085 |
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