Nitroglycerin Tolerance in Caveolin-1 Deficient Mice

Nitrate tolerance developed after persistent nitroglycerin (GTN) exposure limits its clinical utility. Previously, we have shown that the vasodilatory action of GTN is dependent on endothelial nitric oxide synthase (eNOS/NOS3) activity. Caveolin-1 (Cav-1) is known to interact with NOS3 on the cytopl...

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Detalhes bibliográficos
Main Authors: Mao, Mao, Varadarajan, Sudhahar, Fukai, Tohru, Bakhshi, Farnaz R., Chernaya, Olga, Dudley, Samuel C., Minshall, Richard D., Bonini, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144835/
https://ncbi.nlm.nih.gov/pubmed/25158065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104101
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