Nitroglycerin Tolerance in Caveolin-1 Deficient Mice

Nitrate tolerance developed after persistent nitroglycerin (GTN) exposure limits its clinical utility. Previously, we have shown that the vasodilatory action of GTN is dependent on endothelial nitric oxide synthase (eNOS/NOS3) activity. Caveolin-1 (Cav-1) is known to interact with NOS3 on the cytopl...

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Hoofdauteurs: Mao, Mao, Varadarajan, Sudhahar, Fukai, Tohru, Bakhshi, Farnaz R., Chernaya, Olga, Dudley, Samuel C., Minshall, Richard D., Bonini, Marcelo G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144835/
https://ncbi.nlm.nih.gov/pubmed/25158065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104101
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