Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway

Nitroglycerin (GTN) has been clinically used to treat angina pectoris and acute heart episodes for over 100 years. The effects of GTN have long been recognized and active research has contributed to the unraveling of numerous metabolic routes capable of converting GTN to the potent vasoactive messen...

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Main Authors: Mao, Mao, Sudhahar, Varadarajan, Ansenberger-Fricano, Kristine, Fernandes, Denise C., Tanaka, Leonardo Y., Fukai, Tohru, Laurindo, Francisco R.M., Mason, Ronald P., Vasquez-Vivar, Jeannette, Minshall, Richard D., Stadler, Krisztian, Bonini, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432314/
https://ncbi.nlm.nih.gov/pubmed/22037515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.09.020
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