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Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease
Amyloid fibrils composed of peptides as short as six amino acids are effective therapeutics for experimental autoimmune encephalomyelitis (EAE). Immunosuppression arises from at least two pathways: (1) expression of type 1 IFN by pDCs, which were induced by neutrophil extracellular traps arising fro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144739/ https://ncbi.nlm.nih.gov/pubmed/25073790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140107 |
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