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Identification of a common immune regulatory pathway induced by small heat shock proteins, amyloid fibrils, and nicotine
Although certain dogma portrays amyloid fibrils as drivers of neurodegenerative disease and neuroinflammation, we have found, paradoxically, that amyloid fibrils and small heat shock proteins (sHsps) are therapeutic in experimental autoimmune encephalomyelitis (EAE). They reduce clinical paralysis a...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142248/ https://ncbi.nlm.nih.gov/pubmed/29915045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804599115 |
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