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Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease
Amyloid fibrils composed of peptides as short as six amino acids are therapeutic in experimental autoimmune encephalomyelitis (EAE), reducing paralysis and inflammation, while inducing several pathways of immune suppression. Intraperitoneal injection of fibrils selectively activates B-1a lymphocytes...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679000/ https://ncbi.nlm.nih.gov/pubmed/26621719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521206112 |
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