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An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis

Although the accumulation of amyloidogenic proteins in neuroinflammatory conditions is generally considered pathologic, in a murine model of multiple sclerosis, amyloid-forming fibrils, comprised of hexapeptides, are anti-inflammatory. Whether these molecules modulate systemic inflammatory condition...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mahapatra, Sidharth, Ying, Lihua, Ho, Peggy Pui-Kay, Kurnellas, Michael, Rothbard, Jonathan, Steinman, Lawrence, Cornfield, David N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039005/
https://ncbi.nlm.nih.gov/pubmed/29990318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199206
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