MTOR KINASE INHIBITORS AND APOPTOSIS IN GLIOBLASTOMA

BACKGROUND: Glioblastoma represents the most common primary brain tumor, and among the most lethal of cancers. The axis linking receptor tyrosine kinases and phosphatidylinositol 3' kinase to the mammalian target of rapamycin (mTOR) is activated in a majority of glioblastomas, suggesting mTOR a...

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Detalhes bibliográficos
Main Authors: Weiss, William A., Wong, Robyn, Fan, Qi-Wen, Ilkhanizadeh, Shirin, Lu, Mimi, Beyer, Janine, Dube, Nikhil, Forsayeth, John, Kells, Adrian, Xu, Ting, Bankiewicz, Krystof, Ducker, Greg, Feldman, Morri, Shokat, Kevan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144577/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.31
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