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Proton transfers in the Strecker reaction revealed by DFT calculations

The Strecker reaction of acetaldehyde, NH(3), and HCN to afford alanine was studied by DFT calculations for the first time, which involves two reaction stages. In the first reaction stage, the aminonitrile was formed. The rate-determining step is the deprotonation of the NH(3)(+) group in MeCH(OH)-N...

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Autori principali: Yamabe, Shinichi, Zeng, Guixiang, Guan, Wei, Sakaki, Shigeyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143099/
https://ncbi.nlm.nih.gov/pubmed/25161735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.184
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