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Proton transfers in the Strecker reaction revealed by DFT calculations

The Strecker reaction of acetaldehyde, NH(3), and HCN to afford alanine was studied by DFT calculations for the first time, which involves two reaction stages. In the first reaction stage, the aminonitrile was formed. The rate-determining step is the deprotonation of the NH(3)(+) group in MeCH(OH)-N...

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Bibliografiske detaljer
Main Authors: Yamabe, Shinichi, Zeng, Guixiang, Guan, Wei, Sakaki, Shigeyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143099/
https://ncbi.nlm.nih.gov/pubmed/25161735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.184
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