Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

Recent studies have demonstrated that thymus-derived naturally occurring CD4(+)Foxp3(+) regulatory T cells (Tregs) in human and mouse may be unstable and dysfunctional in the presence of proinflammatory cytokines. All-trans RA (atRA), the active derivative of vitamin A, has been shown to regulate Tr...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lu, Ling, Lan, Qin, Li, Zhiyuan, Zhou, Xiaohui, Gu, Jian, Li, Qiang, Wang, Julie, Chen, Maogen, Liu, Ya, Shen, Yi, Brand, David D., Ryffel, Bernhard, Horwitz, David A., Quismorio, Francisco P., Liu, Zhongmin, Li, Bin, Olsen, Nancy J., Zheng, Song Guo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143025/
https://ncbi.nlm.nih.gov/pubmed/25099355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408780111
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi