Phenotypic and functional characteristic of a newly identified CD8(+)Foxp3(−)CD103(+) regulatory T cells

TGF-β and Foxp3 expressions are crucial for the induction and functional activity of CD4(+)Foxp3(+) regulatory T (iTreg) cells. Here, we demonstrate that although TGF-β-primed CD8(+) cells display much lower Foxp3 expression, their suppressive capacity is equivalent to that of CD4(+) iTreg cells, an...

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Detalhes bibliográficos
Main Authors: Liu, Ya, Lan, Qin, Lu, Ling, Chen, Maogen, Xia, Zanxian, Ma, Jilin, Wang, Julie, Fan, Huimin, Shen, Yi, Ryffel, Bernhard, Brand, David, Quismorio, Francisco, Liu, Zhongmin, Horwitz, David A., Xu, Anping, Zheng, Song Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927769/
https://ncbi.nlm.nih.gov/pubmed/23861553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjt026
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