Differential role of all-trans retinoic acid in promoting the development of CD4(+) and CD8(+) regulatory T cells

It is known that ATRA promotes the development of TGF-β-induced CD4(+)Foxp3(+) iTregs, which play a vital role in the prevention of autoimmune diseases; however, the role of ATRA in facilitating the differentiation and function of CD8(+)Foxp3(+) iTregs remains elusive. Using a head-to-head compariso...

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Autores principales: Ma, Jilin, Liu, Ya, Li, Yang, Gu, Jian, Liu, Justin, Tang, Jiayou, Wang, Julie, Ryffel, Bernhard, Shen, Yi, Brand, David, Liu, Zhongmin, Zheng, Song Guo
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Leukocyte Biology 2014
Materias:
Cell Development, Differentiation, & Trafficking
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896662/
https://ncbi.nlm.nih.gov/pubmed/24082012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0513297
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