Core structure of the U6 snRNP at 1.7 Å resolution

The spliceosome is a dynamic assembly of five small nuclear ribonucleoproteins (snRNPs) that removes introns from eukaryotic pre-mRNA. U6 is the most conserved of the spliceosomal snRNAs and participates directly in catalysis. Here, we report the crystal structure of the Saccharomyces cerevisiae U6...

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Bibliographic Details
Main Authors: Montemayor, Eric J., Curran, Elizabeth C., Liao, Hong Hong, Andrews, Kristie L., Treba, Christine N., Butcher, Samuel E., Brow, David A.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141773/
https://ncbi.nlm.nih.gov/pubmed/24837192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2832
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