Motor and cognitive deficits in aged tau knockout mice in two background strains

BACKGROUND: We recently reported that Parkinsonian and dementia phenotypes emerge between 7-12 months of age in tau(-/-) mice on a Bl6/129sv mixed background. These observations were partially replicated by another group using pure Bl6 background tau(-/-) mice, but notably they did not observe a cog...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lei, Peng, Ayton, Scott, Moon, Steve, Zhang, Qihao, Volitakis, Irene, Finkelstein, David I, Bush, Ashley I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141346/
https://ncbi.nlm.nih.gov/pubmed/25124182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-29
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