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Age-appropriate cognition and subtle dopamine-independent motor deficits in aged Tau knockout mice

The microtubule-associated protein tau is expressed throughout the nervous system, most highly in neurons but also in glial cells. Its functions in adult and aging mammals remain to be defined. Previous studies in mouse models found either protective or detrimental effects of genetic tau ablation. W...

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Detalhes bibliográficos
Main Authors: Morris, Meaghan, Hamto, Patricia, Adame, Anthony, Devidze, Nino, Masliah, Eliezer, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596503/
https://ncbi.nlm.nih.gov/pubmed/23332171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.12.003
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