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Integrin Receptors on Tumor Cells Facilitate NK cell-mediated Antibody-dependent Cytotoxicity
NK cells that mediate ADCC play an important role in tumor-specific immunity. We have examined factors limiting specific lysis of tumor cells by CD16.NK-92 cells induced by CNTO 95LF antibodies recognizing α(V) integrins that are overexpressed on many tumor cells. Although all tested tumor cells wer...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141007/ https://ncbi.nlm.nih.gov/pubmed/24810893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344179 |
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