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CAN OLIGOMERIC T-CELL RECEPTOR BE USED AS A TOOL TO DETECT VIRAL PEPTIDE EPITOPES ON INFECTED CELLS?
We have utilized soluble HIV Gag-specific T-cell receptor (TCR) D3 with low affinity and TCR-like antibody 25-D1.16 recognizing its natural peptide-MHC (pMHC) ligand with high affinity to determine how affinity and off-rate of the receptor-pMHC interactions affect the sensitivity of pMHC detection o...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632680/ https://ncbi.nlm.nih.gov/pubmed/18845488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.08.025 |
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