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Mechanisms Controlling Granule-mediated Cytolytic Activity of Cytotoxic T Lymphocytes

Cytotoxic T lymphocytes (CTL) play a critical role in the immunity against viruses and cancer. The antigen receptor or T-cell receptor (TCR) on CTL determines the specificity of unwanted cell targeting. The CD8 co-receptor functions in concert with the TCR to enhance TCR-mediated signaling, accounti...

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Dettagli Bibliografici
Autori principali: Anikeeva, Nadia, Sykulev, Yuri
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244531/
https://ncbi.nlm.nih.gov/pubmed/22058021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-011-8252-8
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