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Mechanisms Controlling Granule-mediated Cytolytic Activity of Cytotoxic T Lymphocytes
Cytotoxic T lymphocytes (CTL) play a critical role in the immunity against viruses and cancer. The antigen receptor or T-cell receptor (TCR) on CTL determines the specificity of unwanted cell targeting. The CD8 co-receptor functions in concert with the TCR to enhance TCR-mediated signaling, accounti...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244531/ https://ncbi.nlm.nih.gov/pubmed/22058021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-011-8252-8 |
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