Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7

Cytotoxic T lymphocytes kill infected or malignant cells through the directed release of cytotoxic substances at the site of target cell contact, the immunological synapse. While genetic association studies of genes predisposing to early-onset life-threatening hemophagocytic lymphohistiocytosis has...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chitirala, Praneeth, Ravichandran, Keerthana, Galgano, Donatella, Sleiman, Marwa, Krause, Elmar, Bryceson, Yenan T., Rettig, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692471/
https://ncbi.nlm.nih.gov/pubmed/31447853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01855
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