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Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7

Cytotoxic T lymphocytes kill infected or malignant cells through the directed release of cytotoxic substances at the site of target cell contact, the immunological synapse. While genetic association studies of genes predisposing to early-onset life-threatening hemophagocytic lymphohistiocytosis has...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Chitirala, Praneeth, Ravichandran, Keerthana, Galgano, Donatella, Sleiman, Marwa, Krause, Elmar, Bryceson, Yenan T., Rettig, Jens
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692471/
https://ncbi.nlm.nih.gov/pubmed/31447853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01855
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