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Evidence that the Density of Self Peptide-MHC Ligands Regulates T-Cell Receptor Signaling
Noncognate or self peptide-MHC (pMHC) ligands productively interact with T-cell receptor (TCR) and are always in a large access over the cognate pMHC on the surface of antigen presenting cells. We assembled soluble cognate and noncognate pMHC class I (pMHC-I) ligands at designated ratios on various...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411518/ https://ncbi.nlm.nih.gov/pubmed/22870225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041466 |
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