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Integrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent Manner

Integrin engagement on lymphocytes initiates “outside-in” signaling that is required for cytoskeleton remodeling and the formation of the synaptic interface. However, the mechanism by which the “outside-in” signal contributes to receptor-mediated intracellular signaling that regulates the kinetics o...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Steblyanko, Maria, Anikeeva, Nadia, Campbell, Kerry S., Keen, James H., Sykulev, Yuri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424324/
https://ncbi.nlm.nih.gov/pubmed/25778396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614719
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