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A New Model for Pore Formation by Cholesterol-Dependent Cytolysins
Cholesterol Dependent Cytolysins (CDCs) are important bacterial virulence factors that form large (200–300 Å) membrane embedded pores in target cells. Currently, insights from X-ray crystallography, biophysical and single particle cryo-Electron Microscopy (cryo-EM) experiments suggest that soluble m...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140638/ https://ncbi.nlm.nih.gov/pubmed/25144725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003791 |
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